APOBEC3G Antibody - Cat. #: CSB-PA001926LA01HU

CSB-PA001926LA01HU

Size :50ug

Clone Number:

Aliases:A3G antibody; ABC3G_HUMAN antibody; APOBEC related cytidine deaminase antibody; APOBEC related protein antibody; APOBEC-related cytidine deaminase antibody; APOBEC-related protein 9 antibody; APOBEC-related protein antibody; APOBEC3G antibody; Apolipoprotein B editing enzyme catalytic polypeptide like 3G antibody; Apolipoprotein B mRNA editing enzyme catalytic polypeptide 3G antibody; Apolipoprotein B mRNA editing enzyme catalytic polypeptide like 3G antibody; Apolipoprotein B mRNA editing enzyme catalytic subunit 3G antibody; apolipoprotein B mRNA editing enzyme cytidine deaminase antibody; apolipoprotein B mRNA editing enzyme; catalytic polypeptide-like antibody; ARCD antibody; ARP-9 antibody; ARP9 antibody; bK150C2.7 antibody; CEM-15 antibody; CEM15 antibody; deoxycytidine deaminase antibody; dJ494G10.1 antibody; DNA dC dU editing enzyme APOBEC 3G antibody; DNA dC->dU editing enzyme antibody; DNA dC->dU-editing enzyme APOBEC-3G antibody; EC 3.5.4. antibody; FLJ12740 antibody; MDS019 antibody; OTTHUMP00000028911 antibody; phorbolin-like protein antibody; phorbolin-like protein MDS019 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q9HC16

Immunogen:Recombinant Human DNA dC->dU-editing enzyme APOBEC-3G protein (1-384AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, IHC, IF; Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200

Background:DNA deaminase (cytidine deaminase) which acts as an inhibitor of retrovirus replication and retrotransposon mobility via deaminase-dependent and -independent mechanisms. Exhibits potent antiviral activity against vif-deficient HIV-1. After the penetration of retroviral nucleocapsids into target cells of infection and the initiation of reverse transcription, it can induce the conversion of cytosine to uracil in the minus-sense single-strand viral DNA, leading to G-to-A hypermutations in the subsequent plus-strand viral DNA. The resultant detrimental levels of mutations in the proviral genome, along with a deamination-independent mechanism that works prior to the proviral integration, together exert efficient antiretroviral effects in infected target cells. Selectively targets single-stranded DNA and does not deaminate double-stranded DNA or single-or double-stranded RNA. Exhibits antiviral activity also against simian immunodeficiency viruses (SIVs), hepatitis B virus (HBV), equine infectious anemia virus (EIAV), xenotropic MuLV-related virus (XMRV) and simian foamy virus (SFV). May inhibit the mobility of LTR and non-LTR retrotransposons.

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:Non-conjugated

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:APOBEC3G

Research Areas:Epigenetics and Nuclear Signaling; Immunology; Microbiology