Size :100ul
Clone Number:
Aliases:GRK2, BARK1, BETA-ARK1
Product Type:Monoclonal Antibody
Immunogen Species:Human
UniProt ID:P25098
Immunogen:Purified recombinant human ADRBK1(C-term.) protein fragments expressed in E.coli.
Raised in:Mouse
Species Reactivity:Human,Rat,Mouse,Pig,Dog
Tested Applications:ELISA,WB;Recommended dilution:WB:1:500-1:5000
Background:The product of this gene phosphorylates the beta-2-adrenergic receptor and appears to mediate agonist-specific desensitization observed at high agonist concentrations. Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors, probably inducing a desensitization of them. Key regulator of LPAR1 signaling. Competes with RALA for binding to LPAR1.
Clonality:Monoclonal
Isotype:IgG1
Purification Method:Affinity purified
Conjugate:Non-conjugated
Buffer:Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50%,glycerol
Form:liquid
Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names:ADRBK1
Research Areas:Neuroscience;Signal transduction