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Updated Date: Stock Protein updated on 20171228
Research areas: Signal Transduction
Target / Protein: Sostdc1
Biologically active: Not Tested
Expression system: Mammalian cell
Species of origin: Rattus norvegicus (Rat)
Delivery time: 3-7 business days
Uniprot ID: Q642G2
AA Sequence: FKNDATEILYSHVVKPVSAHPSSNSTLNQARNGGRHFSSTGLDRNSRVQVGCRELRSTKYISDGQCTSISPLKELVCAGECLPLPVLPNWIGGGYGTKYWSRRSSQEWRCVNDKTRTQRIQLQCQDGSTRTYKITVVTACKCKRYTRQHNESSHNFESVSPAKPAQHHRERKRASKSSKHSLS
Tag info: N-terminal 10xHis-tagged and C-terminal Myc-tagged
Expression Region: 24-206aa
Protein length: Full Length of Mature Protein
MW: 24.6 kDa
Alternative Name(s): Uterine sensitization-associated gene 1 protein
Relevance: Directly antagonizes activity of BMP2, BMP4, BMP6 and BMP7 in a dose-dependent manner. May be involved in the onset of endometrial receptivity for implantation/sensitization for the decidual cell reaction. Enhances Wnt signaling and inhibits TGF-beta signaling.
Reference: "Uterine sensitization-associated gene-1: a novel gene induced within the rat endometrium at the time of uterine receptivity/sensitization for the decidual cell reaction." Simmons D.G., Kennedy T.G. Biol. Reprod. 67:1638-1645(2002)
Purity: Greater than 85% as determined by SDS-PAGE.
Storage: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20℃/-80℃. The shelf life of lyophilized form is 12 months at -20℃/-80℃.
Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.