Size :100ul
Clone Number:
Aliases:homolog of B; RAD23B; RD23B_HUMAN; UV excision repair protein RAD23 homolog B; XP C repair complementing complex 58 kDa; XP C repair complementing complex 58 kDa protein; XP C repair complementing protein; XP-C repair-complementing complex 58 kDa protein;
Product Type:Monoclonal Antibody
Immunogen Species:Human
UniProt ID:P54727
Immunogen:Purified recombinant human hHR23b protein fragments expressed in E.coli.
Raised in:Mouse
Species Reactivity:Human,Mouse,Rat,Monkey,Hamster
Tested Applications:ELISA,WB,IHC,ICC;Recommended dilution:WB:1:500-1:5000,IHC:1:50-1:500,ICC:1:50-1:200
Background:Multiubiquitin chain receptor involved in modulation of proteasomal degradation. Binds to polyubiquitin chains. Proposed to be capable to bind simultaneously to the 26S proteasome and to polyubiquitinated substrates and to deliver ubiquitinated proteins to the proteasome. May play a role in endoplasmic reticulum-associated degradation (ERAD) of misfolded glycoproteins by association with PNGase and delivering deglycosylated proteins to the proteasome.
Clonality:Monoclonal
Isotype:IgG2b
Purification Method:Affinity purified
Conjugate:Non-conjugated
Buffer:Purified mouse monoclonal antibody in PBS(pH 7.4) containing with 0.02% sodium azide and 50% glycerol.
Form:liquid
Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names:RAD23B
Research Areas:Epigenetics and Nuclear Signaling