RAB27A Antibody - Cat. #: CSB-RA285197A0HU

RAB27A Antibody - Cat. #: CSB-RA285197A0HU

CSB-RA285197A0HU
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Size :50ul

Clone Number:2E8

Aliases:Ras-related protein Rab-27A (Rab-27) (GTP-binding protein Ram), RAB27A, RAB27

Product Type:Recombinant Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:P51159

Immunogen:A synthesized peptide derived from human RAB27A

Raised in:

Species Reactivity:Human

Tested Applications:ELISA, FC; Recommended dilution: FC:1:50-1:200

Background:Small GTPase which cycles between active GTP-bound and inactive GDP-bound states. In its active state, binds to a variety of effector proteins to regulate homeostasis of late endocytic pathway, including endosomal positioning, maturation and secretion (PubMed:30771381). Plays a role in cytotoxic granule exocytosis in lymphocytes. Required for both granule maturation and granule docking and priming at the immunologic synapse. {ECO:0000269|PubMed:18812475, ECO:0000269|PubMed:30771381}.

Clonality:Monoclonal

Isotype:Rabbit IgG

Purification Method:Affinity-chromatography

Conjugate:Non-conjugated

Buffer:Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:RAB27A

Research Areas:Signal transduction

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