
Size :50ul
Clone Number:2E8
Aliases:Ras-related protein Rab-27A (Rab-27) (GTP-binding protein Ram), RAB27A, RAB27
Product Type:Recombinant Antibody
Immunogen Species:Homo sapiens (Human)
UniProt ID:P51159
Immunogen:A synthesized peptide derived from human RAB27A
Raised in:
Species Reactivity:Human
Tested Applications:ELISA, FC; Recommended dilution: FC:1:50-1:200
Background:Small GTPase which cycles between active GTP-bound and inactive GDP-bound states. In its active state, binds to a variety of effector proteins to regulate homeostasis of late endocytic pathway, including endosomal positioning, maturation and secretion (PubMed:30771381). Plays a role in cytotoxic granule exocytosis in lymphocytes. Required for both granule maturation and granule docking and priming at the immunologic synapse. {ECO:0000269|PubMed:18812475, ECO:0000269|PubMed:30771381}.
Clonality:Monoclonal
Isotype:Rabbit IgG
Purification Method:Affinity-chromatography
Conjugate:Non-conjugated
Buffer:Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form:Liquid
Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names:RAB27A
Research Areas:Signal transduction