Size :100ul
Clone Number:
Aliases:PPARGC1A; LEM6; PGC1; PGC1A; PGC-1v; PPARGC1; PGC-1(alpha)
Product Type:Monoclonal Antibody
Immunogen Species:Human
UniProt ID:Q9UBK2
Immunogen:Purified recombinant fragment of human PGC-1alpha expressed in E. Coli
Raised in:Mouse
Species Reactivity:Human
Tested Applications:ELISA,WB;Recommended dilution:WB:1:500-1:5000
Background:The protein encoded by this gene is a transcriptional coactivator that regulates the genes involved in energy metabolism. This protein interacts with PPAR gamma, which permits the interaction of this protein with multiple transcription factors. This protein can interact with, and regulate the activities of, cAMP response element binding protein (CREB) and nuclear respiratory factors (NRFs). It provides a direct link between external physiological stimuli and the regulation of mitochondrial biogenesis, and is a major factor that regulates muscle fiber type determination. This protein may be also involved in controlling blood pressure, regulating cellular cholesterol homoeostasis, and the development of obesity. "
Clonality:Monoclonal
Isotype:IgG1
Purification Method:Affinity-chromatography
Conjugate:Non-conjugated
Buffer:Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 ?C.Stable for 12 months from date of receipt
Form:liquid
Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names:PPARGC1A
Research Areas:Epigenetics and Nuclear Signaling;Cancer?Cardiovascular;Metabolism