Phospho-FOXO3 (S253) Antibody - Cat. #: CSB-RA008836A253phHU

CSB-RA008836A253phHU

Size :50ul

Clone Number:1E1

Aliases:Forkhead box protein O3, AF6q21 protein, FOXO3

Product Type:Recombinant Antibody

Immunogen Species:Human

UniProt ID:O43524

Immunogen:A synthesized peptide derived from human Phospho-FOXO3 (S253)

Raised in:

Species Reactivity:Human

Tested Applications:ELISA, WB, IHC; Recommended dilution: WB:1:500-1:5000, IHC:1:50-1:200

Background:Transcriptional activator which triggers apoptosis in the absence of survival factors, including neuronal cell death upon oxidative stress. Recognizes and binds to the DNA sequence 5'-[AG]TAAA[TC]A-3'. Participates in post-transcriptional regulation of MYC: following phosphorylation by MAPKAPK5, promotes induction of miR-34b and miR-34c expression, 2 post-transcriptional regulators of MYC that bind to the 3'UTR of MYC transcript and prevent its translation.

Clonality:Monoclonal

Isotype:Rabbit IgG

Purification Method:Affinity-chromatography

Conjugate:Non-conjugated

Buffer:Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:FOXO3

Research Areas:Epigenetics and Nuclear Signaling