Size :100ul
Clone Number:
Aliases:EDR, HB-1, Mar2, MEF3L, Mart2, RGAG3
Product Type:Monoclonal Antibody
Immunogen Species:Human
UniProt ID:Q86TG7
Immunogen:Purified recombinant human PEG10 protein fragments expressed in E.coli.
Raised in:Mouse
Species Reactivity:Human,Mouse,Rabbit,Pig
Tested Applications:ELISA,WB,IP;Recommended dilution:WB:1:500-1:5000,IP:1:200-1:2000
Background:This is a paternally expressed imprinted gene that encodes transcripts containing two overlapping open reading frames (ORFs), RF1 and RF1/RF2, as well as retroviral-like slippage and pseudoknot elements, which can induce a -1 nucleotide frame-shift. Prevents apoptosis in hepatocellular carcinoma (HCC) cells through interaction with SIAH1, a mediator of apoptosis. May also have a role in cell growth promotion and hepatoma formation.
Clonality:Monoclonal
Isotype:IgG1
Purification Method:Affinity purified
Conjugate:Non-conjugated
Buffer:Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50%,glycerol
Form:liquid
Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names:PEG10
Research Areas:Epigenetics and Nuclear Signaling;Cancer;Stem cells