
Size:100ug
Purification:Immunogen affinity purified
Form:liquid
Purity:?95% as determined by SDS-PAGE
Host:Rabbit
Clonality:polyclonal
Clone ID:
Isotype:IgG
Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)
Background:The natural cytotoxicity receptors (NCRs) are a recently characterized family of Ig-like activation receptors that appear to be major triggering receptors in tumor cell recognition. NCR1 is a glycoprotein that has two extracellular Ig-like domains followed by a ~40 amino acid residue stalk region, a type I transmembrane domain, and a short cytoplasmic tail. NCR1 has been shown to represent a novel NK cell-specific molecule involved in human NK cell activation. NCR1 has been implicated in NK cell-mediated lysis of several autologous tumor cells and pathogen-infected cell lines.
Immunogen:Natural cytotoxicity triggering receptor 1
Synonyms:CD335, LY94, NK-p46, NKP46, NCR1
Observed MW:46 kDa
Uniprot ID:O76036
Reactivity:Human, Mouse
Tested Application:ELISA, WB, IHC, IF
Recommended dilution:WB: 1:500-1:2000; IHC: 1:50-1:200; IF: 1:50-1:200
Gene ID:9437
Research Area: