NCR1 antibody , Cat. #  FNab10472

NCR1 antibody , Cat. # FNab10472

FNab10472
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Size:100ug

Purification:Immunogen affinity purified

Form:liquid

Purity:?95% as determined by SDS-PAGE

Host:Rabbit

Clonality:polyclonal

Clone ID:

Isotype:IgG

Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)

Background:The natural cytotoxicity receptors (NCRs) are a recently characterized family of Ig-like activation receptors that appear to be major triggering receptors in tumor cell recognition. NCR1 is a glycoprotein that has two extracellular Ig-like domains followed by a ~40 amino acid residue stalk region, a type I transmembrane domain, and a short cytoplasmic tail. NCR1 has been shown to represent a novel NK cell-specific molecule involved in human NK cell activation. NCR1 has been implicated in NK cell-mediated lysis of several autologous tumor cells and pathogen-infected cell lines.

Immunogen:Natural cytotoxicity triggering receptor 1

Synonyms:CD335, LY94, NK-p46, NKP46, NCR1

Observed MW:46 kDa

Uniprot ID:O76036

Reactivity:Human, Mouse

Tested Application:ELISA, WB, IHC, IF

Recommended dilution:WB: 1:500-1:2000; IHC: 1:50-1:200; IF: 1:50-1:200

Gene ID:9437

Research Area:

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