
Size :50ug
Clone Number:
Aliases:5 HT 2 antibody; 5 HT 2A antibody; 5 HT2 receptor antibody; 5 HT2A antibody; 5 hydroxytryptamine receptor 2A antibody; 5-HT-2 antibody; 5-HT-2A antibody; 5-hydroxytryptamine (serotonin) receptor 2A; G protein-coupled antibody; 5-hydroxytryptamine 2A receptor antibody; 5-hydroxytryptamine receptor 2A antibody; 5HT2A_HUMAN antibody; HTR 2 antibody; HTR 2A antibody; HTR2 antibody; HTR2; formerly antibody; HTR2A antibody; serotonin 5-HT-2 receptor; formerly antibody; serotonin 5-HT-2A receptor antibody; Serotonin receptor 2A antibody
Product Type:Polyclonal Antibody
Immunogen Species:Homo sapiens (Human)
UniProt ID:P28223
Immunogen:Recombinant Human 5-hydroxytryptamine receptor 2A protein (385-471AA)
Raised in:Rabbit
Species Reactivity:Human
Tested Applications:ELISA
Background:G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various drugs and psychoactive substances, including mescaline, psilocybin, 1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane (DOI) and lysergic acid diethylamide (LSD). Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Beta-arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. Signaling activates phospholipase C and a phosphatidylinositol-calcium second messenger system that modulates the activity of phosphatidylinositol 3-kinase and promotes the release of Ca2+ ions from intracellular stores. Affects neural activity, perception, cognition and mood. Plays a role in the regulation of behavior, including responses to anxiogenic situations and psychoactive substances. Plays a role in intestinal smooth muscle contraction, and may play a role in arterial vasoconstriction.
Clonality:Polyclonal
Isotype:IgG
Purification Method:>95%, Protein G purified
Conjugate:HRP
Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form:Liquid
Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names:HTR2A
Research Areas:Neuroscience; Metabolism
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