GAD1 Antibody - Cat. #: CSB-PA981570

CSB-PA981570

Size :50ul

Clone Number:

Aliases:67 kDa glutamic acid decarboxylase antibody; CPSQ1 antibody; DCE1 antibody; DCE1_HUMAN antibody; EC 4.1.1.15 antibody; FLJ45882 antibody; GAD 1 antibody; GAD 67 antibody; GAD antibody; GAD-67 antibody; GAD1 antibody; Glutamate decarboxylase 1 (brain; 67kDa) antibody; Glutamate decarboxylase 1 antibody; Glutamate decarboxylase 1 brain 67kD antibody; Glutamate decarboxylase 1 brain 67kDa antibody; Glutamate decarboxylase 67 kDa isoform antibody; Glutamate decarboxylase; brain; 67-KD antibody; OTTHUMP00000041054 antibody; OTTHUMP00000041055 antibody; OTTHUMP00000228572 antibody; SCP antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q99259

Immunogen:Synthetic peptide of Human GAD1

Raised in:Rabbit

Species Reactivity:Human, Mouse, Rat

Tested Applications:ELISA, WB, IHC; ELISA:1:1000-1:2000, WB:1:200-1:1000, IHC:1:25-1:100

Background:This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantigen and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Deficiency in this enzyme has been shown to lead to pyridoxine dependency with seizures. Alternative splicing of this gene results in two products, the predominant 67-kD form and a less-frequent 25-kD form.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen affinity purification

Conjugate:Non-conjugated

Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:GAD1

Research Areas:Immunology?Metabolism;Signal transduction