Size :50ug
Clone Number:2E11B6
Aliases:CD59 glycoprotein,HRF-20,MAC-IP,MACIF,MIRL,CD59
Product Type:Monoclonal Antibody
Immunogen Species:Human
UniProt ID:P13987
Immunogen:Recombinant CD59 Protein
Raised in:Mouse
Species Reactivity:Human
Tested Applications:ELISA,WB,IHC;Recommended dilution:WB:1:500-1:5000,IHC:1:50-1:500
Background:CD59, also named as MIC11, MIN1, MIN2, MIN3, MSK21, MIRL, MACIF, HRF20 and 1F5 antigen, is a cell surface molecule glycoprotein with MW 18-25kd. It acts as a determinant of proximal–distal cell identity. CD59 acts by binding to the C8 and/or C9 complements of the assembling membrane attack complex (MAC), thereby preventing incorporation of the multiple copies of C9 required for complete formation of the osmolytic pore. It is involved in signal transduction for T-cell activation complexed to a protein tyrosine kinase.
Clonality:Monoclonal
Isotype:IgG1
Purification Method:>95%,Protein G purified
Conjugate:Non-conjugated
Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form:liquid
Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names:CD59
Research Areas:Cardiovascular;Immunology;Signal transduction?Stem cells