Size :100ul
Clone Number:
Aliases:
Product Type:Monoclonal Antibody
Immunogen Species:Human
UniProt ID:P08571
Immunogen:Recombinant Protein
Raised in:Mouse
Species Reactivity:Human
Tested Applications:ELISA,IF,FC;Recommended dilution:IF:1:100-1:200
Background:4AW4 reacts with CD14, a 53-55 kDa molecule. CD14 is a human high affinity cell-surface receptor for complexes of lipopolysaccharide (LPS-endotoxin) and serum LPS-binding protein (LPB). CD14 antigen has a strong presence on the surface of monocytes/macrophages, is weakly expressed on granulocytes, but not expressed by myeloid progenitor cells. CD14 functions as a receptor for endotoxin; when the monocytes become activated they release cytokines such as TNF, and up-regulate cell surface molecules including adhesion molecules.This clone is cross reactive with non-human primate.1. Knapp, W et al., eds. (1989) Leucocyte Typing IV: White Cell Differentiation Antigens, Oxford University Press, New York.2. Makgoba, MW et al., (1988) Nature 331: 86-883. Boyd. AW et al. (1989) Blood 73: 1896-1903
Clonality:Monoclonal
Isotype:IgG1
Purification Method:Affinity purified
Conjugate:Non-conjugated
Buffer:Phosphate-buffered solution, pH 7.4, containing 0.09% sodium azide and 0.2% (w/v) BSA
Form:liquid
Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names:CD14
Research Areas:Immunology;Stem cells