ZNRF3 Antibody, Biotin conjugated - Cat. #: CSB-PA890933HD01HU

CSB-PA890933HD01HU

Size :50ug

Clone Number:

Aliases:ZNRF3 antibody; KIAA1133 antibody; RNF203 antibody; E3 ubiquitin-protein ligase ZNRF3 antibody; EC 2.3.2.27 antibody; RING finger protein 203 antibody; RING-type E3 ubiquitin transferase ZNRF3 antibody; Zinc/RING finger protein 3 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q9ULT6

Immunogen:Recombinant Human E3 ubiquitin-protein ligase ZNRF3 protein (56-219AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA

Background:E3 ubiquitin-protein ligase that acts as a negative regulator of the Wnt signaling pathway by mediating the ubiquitination and subsequent degradation of Wnt receptor complex components Frizzled and LRP6. Acts on both canonical and non-canonical Wnt signaling pathway. Acts as a tumor suppressor in the intestinal stem cell zone by inhibiting the Wnt signaling pathway, thereby resticting the size of the intestinal stem cell zone.

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:Biotin

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:ZNRF3

Research Areas:Epigenetics and Nuclear Signaling