Size:100ug. Other sizes are also available. Please contact us.
Research Areas:Immunology
Uniprot NO.:P05000
Uniprot Entry Name:IFNW1_HUMAN
Gene Names:IFNW1
Species:Homo sapiens (Human)
Source:E.Coli
Expression Region:24-195aa
Sequence:CDLPQNHGLL SRNTLVLLHQ MRRISPFLCL KDRRDFRFPQ EMVKGSQLQK AHVMSVLHEM LQQIFSLFHT ERSSAAWNMT LLDQLHTGLH QQLQHLETCL LQVVGEGESA GAISSPALTL RRYFQGIRVY LKEKKYSDCA WEVVRMEIMK SLFLSTNMQE RLRSKDRDLG SS
Protein Description:Partial
Tag Info:Tag-Free
Mol. Weight:20.0 kDa
Biological_Activity:Fully biologically active when compared to standard. The ED50 as determined by a chemotaxis bioassay using human TF-1 cells is less than 0.01 ng/ml, corresponding to a specific activity of ? 1.0 × 108 IU/mg.
Purity:>97% as determined by SDS-PAGE and HPLC.
Endotoxin:Less than 1.0 EU/µg as determined by LAL method.
Form:Lyophilized powder
Buffer:Lyophilized from a 0.2 µm filtered PBS, pH 7.4
Reconstitution:We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20?/-80?. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Notes:Repeated freezing and thawing is not recommended. Store working aliquots at 4? for up to one week.
Alternative Name/ Alias:Interferon alpha-II-1,
Relevance:
PubMed ID:2985969; 1647209; 15164053; 15489334; 3895159; 8142025; 7765487; 15340161; 1693148; 21854986
Function:
Involvement in disease:
Subcellular Location:Secreted
Protein Families:Alpha/beta interferon family
Tissue Specificity:
Paythway:Jak-STATsignalingpathway
HGNC Database Link:https://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=HGNC:5448
UniGene Database Link:https://www.ncbi.nlm.nih.gov/UniGene/clust.cgi?ORG=Hs&CID=73010
KEGG Database Link:https://www.genome.jp/dbget-bin/www_bget?hsa:3467
STRING Database Link:https://string-db.org/network/9606.ENSP00000369578
OMIM Database Link:https://www.omim.org/entry/147553147553147553