Size:20ug. Other sizes are also available. For further information, please contact us.
Research Areas:Others
Uniprot ID:Q5J8M3
Gene Names:EMC4
Organism:Homo sapiens (Human)
AA Sequence:TAQGGLVANRGRRFKWAIELSGPGGGSRGRSDRGSGQGDSLYPVGYLDKQVPDTSVQETDRILVEKRCWDIALGPLKQIPMNLFIMYMAGNTISIFPTMMVCMMAWRPIQALMAISATFKMLESSSQKFLQGLVYLIGNLMGLALAVYKCQSMGLLPTHASDWLAFIEPPERMEFSGGGLLL
Expression Region:2-183aa
Sequence Info:Full Length of Mature Protein
Source:in vitro E.coli expression system
Tag Info:N-terminal 10xHis-tagged
MW:26.0 kDa
Alternative Name(s):Cell proliferation-inducing gene 17 protein (Transmembrane protein 85) (TMEM85)
Relevance:May mediate anti-apoptotic activity.
Reference:"Initial characterization of the human central proteome." Burkard T.R., Planyavsky M., Kaupe I., Breitwieser F.P., Buerckstuemmer T., Bennett K.L., Superti-Furga G., Colinge J. BMC Syst. Biol. 5:17-17(2011)
Purity:Greater than 85% as determined by SDS-PAGE.
Form:Liquid or Lyophilized powder
Buffer:If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
Reconstitution:We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20?/-80?. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Storage:The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20?/-80?. The shelf life of lyophilized form is 12 months at -20?/-80?.
Notes:Repeated freezing and thawing is not recommended. Store working aliquots at 4? for up to one week.
Function:May mediate anti-apoptotic activity.
Involvement in disease:
Subcellular Location:Membrane, Multi-pass membrane protein
Protein Families:EMC4 family
Tissue Specificity:Isoform 1 is expressed in brain and heart. Isoform 2 is expressed in heart.
Paythway:
HGNC Database Link:https://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=HGNC:28032
UniGene Database Link:https://www.ncbi.nlm.nih.gov/UniGene/clust.cgi?ORG=Hs&CID=250905
KEGG Database Link:https://www.genome.jp/dbget-bin/www_bget?hsa:51234
STRING Database Link:https://string-db.org/network/9606.ENSP00000267750
OMIM Database Link:https://www.omim.org/entry/616245616245616245
Lead Time Guidance:3-7 business days