Size:100ug. Other sizes are also available. Please contact us.
Research Areas:Immunology
Uniprot NO.:Q9Y258
Uniprot Entry Name:CCL26_HUMAN
Gene Names:CCL26,SCYA26,UNQ216/PRO242
Species:Homo sapiens (Human)
Source:E.Coli
Expression Region:24-94aa
Sequence:TRGSDISKTC CFQYSHKPLP WTWVRSYEFT SNSCSQRAVI FTTKRGKKVC THPRKKWVQK YISLLKTPKQ L
Protein Description:Full Length of Mature Protein
Tag Info:Tag-Free
Mol. Weight:8.4 kDa
Biological_Activity:Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human CCR3 transfected HEK293 cells is in a concentration range of 0.5- 2.0 ?g/ml.
Purity:>97% as determined by SDS-PAGE and HPLC.
Endotoxin:Less than 1.0 EU/µg as determined by LAL method.
Form:Lyophilized powder
Buffer:Lyophilized from a 0.2 µm filtered PBS, pH 7.4
Reconstitution:We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20?/-80?. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Notes:Repeated freezing and thawing is not recommended. Store working aliquots at 4? for up to one week.
Alternative Name/ Alias:CC chemokine IMAC, Macrophage inflammatory protein 4-alpha, MIP-4-alpha, Small-inducible cytokine A26, Thymic stroma chemokine-1
Relevance:Chemotactic for eosinophils and basophils. Binds to CCR3.
PubMed ID:10373330; 10415065; 10488147; 12975309; 12853948; 15489334; 11425309
Function:Chemoattractant for eosinophils and basophils
Involvement in disease:
Subcellular Location:Secreted
Protein Families:Intercrine beta (chemokine CC) family
Tissue Specificity:Ubiquitously expressed at low levels in various tissues including heart and ovary.
Paythway:Chemokinesignalingpathway
HGNC Database Link:https://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=HGNC:10625
UniGene Database Link:https://www.ncbi.nlm.nih.gov/UniGene/clust.cgi?ORG=Hs&CID=131342
KEGG Database Link:https://www.genome.jp/dbget-bin/www_bget?hsa:10344
STRING Database Link:https://string-db.org/network/9606.ENSP00000005180
OMIM Database Link:https://www.omim.org/entry/604697604697604697