Size :100ul
Clone Number:
Aliases:
Product Type:Monoclonal Antibody
Immunogen Species:Human
UniProt ID:P13591
Immunogen:Recombinant Protein
Raised in:Mouse
Species Reactivity:Human
Tested Applications:ELISA,IF,FC;Recommended dilution:IF:1:100-1:200
Background:COC56 reacts with CD56, a 175-220 kDa Neural Cell Adhesion Molecule (NCAM), expressed on 10-25% of peripheral blood lymphocytes, including all CD16+ NK cells and approximately 5% of CD3+ lymphocytes, referred to as NKT cells. It also is present at brain and neuromuscular junctions, certain LGL leukemias, small cell lung carcinomas, neuronally derived tumors, myeloma and myeloid leukemias. CD56 (NCAM) is involved in neuronal homotypic cell adhesion which is implicated in neural development, and in cell differentiation during embryogenesis.1. Knapp, W et al., eds. (1989) Leucocyte Typing IV: White Cell Differentiation Antigens, Oxford University Press, New York.2. Lanier LL . et al. (1991) J. Immunol. 146:4421-4426.3. Campbell, JJ et al. (2001) J. Immunol . 166:6477-6482.4. Cooper MD et al. (2001) Trends in Immunol. 22:633-640.5. Galandrini R et al. (2002) Blood. 100:4581-4589.
Clonality:Monoclonal
Isotype:IgG1
Purification Method:Affinity purified
Conjugate:Non-conjugated
Buffer:Phosphate-buffered solution, pH 7.4, containing 0.09% sodium azide and 0.2% (w/v) BSA
Form:liquid
Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names:NCAM1
Research Areas:Neuroscience;Signal transduction?Stem cells