Size :50ug
Clone Number:15E7B4
Aliases:CRP
Product Type:Monoclonal Antibody
Immunogen Species:Human
UniProt ID:P02741
Immunogen:Recombinant Human CRP Protein
Raised in:Mouse
Species Reactivity:Human
Tested Applications:ELISA,IHC;Recommended dilution:IHC:1:50-1:500
Background:"C-reactive protein (CRP) is an annular (ring-shaped), pentameric protein found in blood plasma, the levels of which rise in response to inflammation (i.e., C-reactive protein is an acute-phase protein of hepatic origin that increases following interleukin-6 secretion from macrophages and T cells). Its physiological role is to bind to lysophosphatidylcholine expressed on the surface of dead or dying cells (and some types of bacteria) in order to activate the complement system via the C1Q complex. CRP is synthesized by the liver in response to factors released by macrophages and fat cells (adipocytes).It is a member of the pentraxin family of proteins.It is not related to C-peptide (insulin) or protein C (blood coagulation). C-reactive protein was the first pattern recognition receptor (PRR) to be identified."
Clonality:Monoclonal
Isotype:IgG
Purification Method:>95%,Protein G purified
Conjugate:Non-conjugated
Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form:liquid
Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names:CRP
Research Areas:Epigenetics and Nuclear Signaling;Cardiovascular;Immunology?Metabolism