Size :50ug
Clone Number:3D6H5
Aliases:Ribonucleotide Reductase M1,RRM1,RR1
Product Type:Monoclonal Antibody
Immunogen Species:Human
UniProt ID:P23921
Immunogen:Recombinant Human RRM1 Protein
Raised in:Mouse
Species Reactivity:Human
Tested Applications:ELISA,IHC;Recommended dilution:IHC:1:50-1:500
Background:This gene encodes one of two non-identical subunits that constitute ribonucleoside-diphosphate reductase, an enzyme essential for the production of deoxyribonucleotides prior to DNA synthesis in S phase of dividing cells.It is one of several genes located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor,rhabdomyosarcoma, adrenocrotical carcinoma, and lung, ovarian, and breast cancer. This gene may play a role in malignancies and disease that involve this region.
Clonality:Monoclonal
Isotype:IgG
Purification Method:>95%,Protein G purified
Conjugate:Non-conjugated
Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form:liquid
Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names:RRM1
Research Areas:Epigenetics and Nuclear Signaling