Size:100ug. Other sizes are also available. Please contact us.
Research Areas:Immunology
Uniprot NO.:Q03366
Uniprot Entry Name:CCL7_MOUSE
Gene Names:Ccl7,Fic,Mcp3,Scya7
Species:Mus musculus (Mouse)
Source:E.Coli
Expression Region:24-97aa
Sequence:QPDGPNASTC CYVKKQKIPK RNLKSYRRIT SSRCPWEAVI FKTKKGMEVC AEAHQKWVEE AIAYLDMKTP TPKP
Protein Description:Full Length of Mature Protein
Tag Info:Tag-Free
Mol. Weight:8.5 kDa
Biological_Activity:Fully biologically active when compared to standard. The biologically active determined by a chemotaxis bioassay using human monocytes is in a concentration range of 100-300 ng/ml.
Purity:>95% as determined by SDS-PAGE and HPLC.
Endotoxin:Less than 1.0 EU/µg as determined by LAL method.
Form:Lyophilized powder
Buffer:Lyophilized from a 0.2 µm filtered 2xPBS, pH 7.4
Reconstitution:We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20?/-80?. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Notes:Repeated freezing and thawing is not recommended. Store working aliquots at 4? for up to one week.
Alternative Name/ Alias:Intercrine/chemokine MARC, Monocyte chemotactic protein 3, MCP-3, Protein FIC, Small-inducible cytokine A7
Relevance:Chemotactic factor that attracts monocytes and eosinophils, but not neutrophils. Augments monocyte anti-tumor activity (By similarity). {ECO:0000250}.
PubMed ID:1281219; 8002978; 8455595; 7989769; 10438970; 16141072; 15489334
Function:Chemotactic factor that attracts monocytes and eosinophils, but not neutrophils. Augments monocyte anti-tumor activity (By similarity).
Involvement in disease:
Subcellular Location:Secreted
Protein Families:Intercrine beta (chemokine CC) family
Tissue Specificity:
Paythway:
HGNC Database Link:
UniGene Database Link:https://www.ncbi.nlm.nih.gov/UniGene/clust.cgi?ORG=Mm&CID=341574
KEGG Database Link:https://www.genome.jp/dbget-bin/www_bget?mmu:20306
STRING Database Link:https://string-db.org/network/10090.ENSMUSP00000021011
OMIM Database Link: