Size:100ug. Other sizes are also available. Please contact us.
Research Areas:Immunology
Uniprot NO.:P02778
Uniprot Entry Name:CXL10_HUMAN
Gene Names:CXCL10,INP10,SCYB10
Species:Homo sapiens (Human)
Source:E.Coli
Expression Region:22-98aa (R93M)
Sequence:VPLSRTVRCT CISISNQPVN PRSLEKLEII PASQFCPRVE IIATMKKKGE KRCLNPESKA IKNLLKAVSK EMSKRSP
Protein Description:Full Length of Mature Protein
Tag Info:Tag-Free
Mol. Weight:8.6 kDa
Biological_Activity:Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human peripheral blood T-lymphocytes is in a concentration range of 10- 50 ng/ml.
Purity:>97% as determined by SDS-PAGE and HPLC.
Endotoxin:Less than 1.0 EU/µg as determined by LAL method.
Form:Lyophilized powder
Buffer:Lyophilized from a 0.2 µm filtered 20 mM PB, 50 mM NaCl,pH 7.4
Reconstitution:We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20?/-80?. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Notes:Repeated freezing and thawing is not recommended. Store working aliquots at 4? for up to one week.
Alternative Name/ Alias:10 kDa interferon gamma-induced protein, IP-10, Small-inducible cytokine B10, ,]
Relevance:Chemotactic for monocytes and T-lymphocytes. Binds to CXCR3.
PubMed ID:3925348; 15489334; 8423327; 10233762; 11559369; 18645041; 12173928
Function:Chemotactic for monocytes and T-lymphocytes. Binds to CXCR3.
Involvement in disease:
Subcellular Location:Secreted
Protein Families:Intercrine alpha (chemokine CxC) family
Tissue Specificity:
Paythway:Chemokinesignalingpathway
HGNC Database Link:https://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=HGNC:10637
UniGene Database Link:https://www.ncbi.nlm.nih.gov/UniGene/clust.cgi?ORG=Hs&CID=632586
KEGG Database Link:https://www.genome.jp/dbget-bin/www_bget?hsa:3627
STRING Database Link:https://string-db.org/network/9606.ENSP00000305651
OMIM Database Link:https://www.omim.org/entry/147310147310147310