RECK antibody , Cat. # FNab10074

FNab10074

Size:100ug

Purification:Immunogen affinity purified

Form:liquid

Purity:?95% as determined by SDS-PAGE

Host:Rabbit

Clonality:polyclonal

Clone ID:

Isotype:IgG

Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)

Background:Negatively regulates matrix metalloproteinase-9(MMP-9) by suppressing MMP-9 secretion and by direct inhibition of its enzymatic activity. RECK down-regulation by oncogenic signals may facilitate tumor invasion and metastasis. Appears to also regulate MMP-2 and MT1-MMP, which are involved in cancer progression.

Immunogen:reversion-inducing-cysteine-rich protein with kazal motifs

Synonyms:RECK, ST15, reversion-inducing cysteine-rich protein with Kazal motifs

Observed MW:110 kDa

Uniprot ID:O95980

Reactivity:Human

Tested Application:ELISA, IHC

Recommended dilution:IHC: 1:20-1:200

Gene ID:8434

Research Area:cancer