Size :100ul
Clone Number:
Aliases:EC 3.1.3.16; PP 1G; PP-1G; PP1G; PP1G_HUMAN; PP1gamma; PPP 1G; PPP1CC; PPP1CC protein; PPP1G; Protein phosphatase 1 catalytic subunit gamma isoform; Protein phosphatase 1C catalytic subunit; Protein phosphatase 1C subunit
Product Type:Monoclonal Antibody
Immunogen Species:Human
UniProt ID:P36873
Immunogen:Purified recombinant human PPP1CC protein fragments expressed in E.coli.
Raised in:Mouse
Species Reactivity:Human
Tested Applications:ELISA,WB;Recommended dilution:WB:1:500-1:5000
Background:Protein phosphatase that associates with over 200 regulatory proteins to form highly specific holoenzymes which dephosphorylate hundreds of biological targets.Protein phosphatase 1(PP1)is essential for cell division,and participates in the regulation of glycogen metabolism,muscle contractility and protein synthesis.Dephosphorylates RPS6KB1.Involved in regulation of ionic conductances and long-term synaptic plasticity.May play an important role in dephosphorylating substrates such as the postsynaptic density-associated Ca2+/calmodulin dependent protein kinase II.Component of the PTW/PP1 phosphatase complex,which plays a role in the control of chromatin structure and cell cycle progression during the transition from mitosis into interphase.
Clonality:Monoclonal
Isotype:IgG2b
Purification Method:Affinity purified
Conjugate:Non-conjugated
Buffer:Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine(pH 7.4,150 mM NaCl)with 0.2% sodium azide,0.1mg/mlBSA and 50% glycerol.
Form:liquid
Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names:PPP1CC
Research Areas:Epigenetics and Nuclear Signaling;Cancer;Cell biology;Metabolism;Signal transduction