Size :100ul
Clone Number:
Aliases:PDZD2 antibody; AIPC antibody; KIAA0300 antibody; PDZK3 antibody; PDZ domain-containing protein 2 antibody; Activated in prostate cancer protein antibody; PDZ domain-containing protein 3) [Cleaved into: Processed PDZ domain-containing protein 2] antibody
Product Type:Polyclonal Antibody
Immunogen Species:Homo sapiens (Human)
UniProt ID:O15018
Immunogen:Synthesized peptide derived from internal of Human PDZD2.
Raised in:Rabbit
Species Reactivity:Human, Mouse
Tested Applications:ELISA, IHC, IF; IHC:1:50-1:100, IF:1:100-1:500
Background:Proteins containing PDZ domains have been shown frequently to bind the C-termini of transmembrane receptors or ion channels. They have also been shown to bind to other PDZ domain proteins and could possibly be involved in intracellular signalling. The protein encoded by this gene contains six PDZ domains and shares sequence similarity with pro-interleukin-16 (pro-IL-16). Like pro-IL-16, the encoded protein localizes to the endoplasmic reticulum and is thought to be cleaved by a caspase to produce a secreted peptide containing two PDZ domains. In addition, this gene is upregulated in primary prostate tumors and may be involved in the early stages of prostate tumorigenesis.
Chaib H., Cancer Res. 61:2390-2394(2001).
Nagase T., DNA Res. 4:141-150(1997).
Clonality:Polyclonal
Isotype:IgG
Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Conjugate:Non-conjugated
Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form:liquid
Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names:PDZD2
Research Areas:Neuroscience