Size :50ul
Clone Number:7G7
Aliases:Delta-type opioid receptor (D-OR-1) (DOR-1), OPRD1, OPRD
Product Type:Recombinant Antibody
Immunogen Species:Homo sapiens (Human)
UniProt ID:P41143
Immunogen:A synthesized peptide derived from human OPRD1
Raised in:
Species Reactivity:Human, Mouse
Tested Applications:ELISA, WB; Recommended dilution: WB:1:500-1:5000
Background:G-protein coupled receptor that functions as receptor for endogenous enkephalins and for a subset of other opioids. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling leads to the inhibition of adenylate cyclase activity. Inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance. Plays a role in the perception of pain and in opiate-mediated analgesia. Plays a role in developing analgesic tolerance to morphine.
Clonality:Monoclonal
Isotype:Rabbit IgG
Purification Method:Affinity-chromatography
Conjugate:Non-conjugated
Buffer:Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form:Liquid
Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names:OPRD1
Research Areas:Neuroscience