Size:100ug
Purification:Protein A+G purification
Form:liquid
Purity:?95% as determined by SDS-PAGE
Host:Mouse
Clonality:monoclonal
Clone ID:4E11
Isotype:IgG1
Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)
Background:HSPA8 (also known as HSC70) is a member of the HSPA (HSP70) family of heat-shock proteins which are highly conserved chaperons implicated in protein folding, protein refolding, protein transport, and protein targeting. HSPA8 is a constitutively expressed cytosol/nuclear protein able to translocate between cytoplasm and nucleus. Recently it has been reported that HSPA8 can interact with ?-synuclein, the critical pathological protein of Parkinson’s disease, indicating its implication in neurodegenerative disease. (21832061)
Immunogen:Hsc70
Synonyms:Heat shock 70 kDa protein 8, heat shock 70kDa protein 8, HSC54, Hsc70, HSC71, HSP71, HSP73, HSPA10, HSPA8, LAP1, NIP71
Observed MW:70 kDa
Uniprot ID:P11142
Reactivity:Human, Mouse, Rat
Tested Application:ELISA, WB, IHC
Recommended dilution:WB: 1:3000-1:20000; IHC: 1:50-1:500
Gene ID:3312
Research Area:Neuroscience, Cardiovascular, Metabolism