
Size :50ul
Clone Number:
Aliases:ABCDS antibody; Ednra antibody; EDNRB antibody; EDNRB_HUMAN antibody; Endothelin B receptor antibody; Endothelin B receptor precursor antibody; Endothelin receptor Non selective type antibody; Endothelin receptor non-selective type antibody; Endothelin receptor type B antibody; ET B antibody; ET-B antibody; ET-BR antibody; ETB antibody; ETBR antibody; ETRB antibody; Hirschsprung disease 2 antibody; HSCR antibody; HSCR2 antibody; OTTHUMP00000018534 antibody; OTTHUMP00000178736 antibody; WS4A antibody
Product Type:Polyclonal Antibody
Immunogen Species:Homo sapiens (Human)
UniProt ID:P24530
Immunogen:Synthetic peptide of Human EDNRB
Raised in:Rabbit
Species Reactivity:Human
Tested Applications:ELISA, IHC; ELISA:1:1000-1:2000, IHC:1:50-1:200
Background:The protein encoded by this gene is a G protein-coupled receptor which activates a phosphatidylinositol-calcium second messenger system. Its ligand, endothelin, consists of a family of three potent vasoactive peptides: ET1, ET2, and ET3. Studies suggest that the multigenic disorder, Hirschsprung disease type 2, is due to mutations in the endothelin receptor type B gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Clonality:Polyclonal
Isotype:IgG
Purification Method:Antigen affinity purification
Conjugate:Non-conjugated
Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Form:Liquid
Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names:EDNRB
Research Areas:Signal transduction
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