Size :100ul
Clone Number:
Aliases:15 hydroxyprostaglandin dehydrogenase [NADP+]; 15-hydroxyprostaglandin dehydrogenase [NADP+]; Carbonyl reductase [NADPH] 1; Carbonyl Reductase 1; CBR 1; CBR1; CBR1_HUMAN; CRN; NADPH dependent carbonyl reductase 1; NADPH-dependent carbonyl reductase 1;
Product Type:Monoclonal Antibody
Immunogen Species:Human
UniProt ID:P16152
Immunogen:Purified recombinant human CBR1 protein fragments expressed in E.coli
Raised in:Mouse
Species Reactivity:Human
Tested Applications:ELISA,WB,ICC;Recommended dilution:WB:1:500-1:5000,ICC:1:50-1:200
Background:NADPH-dependent reductase with broad substrate specificity.Catalyzes the reduction of a wide variety of carbonyl compounds including quinones,prostaglandins, menadione,plus various xenobiotics.Catalyzes the reduction of the antitumor anthracyclines doxorubicin and daunorubicin to the cardiotoxic compounds doxorubicinol and daunorubicinol. Can convert prostaglandin E2 to prostaglandin F2-alpha.Can bind glutathione,which explains its higher affinity for glutathione-conjugated substrates.Catalyzes the reduction of S-nitrosoglutathione.
Clonality:Monoclonal
Isotype:IgG1
Purification Method:Affinity purified
Conjugate:Non-conjugated
Buffer:Purified mouse monoclonal in PBS(pH 7.4)containing with 0.2% sodium azide,50% glycerol.
Form:liquid
Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names:CBR1
Research Areas:Cancer;Cell biology;Metabolism;Signal transduction