Size:100ug
Purification:Immunogen affinity purified
Form:liquid
Purity:?95% as determined by SDS-PAGE
Host:Rabbit
Clonality:polyclonal
Clone ID:
Isotype:IgG
Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)
Background:ALOX5(arachidonate 5-lipoxygenase) is also named as LOG5, 5-LO and belongs to the lipoxygenase family. It catalyzes the first step in leukotriene biosynthesis, and plays a role in inflammatory processes. It is a 78 kDa iron-containing enzyme that translocates from the cytosol to associate with FLAP, and converts arachidonate in two steps into the unstable intermediate LTA4. It is essential for cysteinyl-leukotriene(cys-LT) production, critical mediators in asthma(PMID:12911785).
Immunogen:arachidonate 5-lipoxygenase
Synonyms:5 Lipoxygenase, 5 LO, 5 LOX, 5LPG, ALOX5, LOG5
Observed MW:68-78 kDa
Uniprot ID:P09917
Reactivity:Human, Mouse, Rat
Tested Application:ELISA, IF, WB
Recommended dilution:WB: 1:200-1:2000; IF: 1:20-1:100
Gene ID:
Research Area:Metabolism